Tiamulin Hydrogen Fumarate(55297-96-6)
Product Description
● Tiamulin hydrogen fumarate is used for chronic respiratory disease in chickens, Mycoplasma pneumonia and Haemophilus pleuropneumonia in pigs, and also for dysentery caused by Leptospira densa in pigs.
● Properties: white or light yellow crystalline powder; with a slight characteristic odor. Soluble in water (6%), dry product is stable and can be stored for 5 years under seal.
● Tiamulin hydrogen fumarate is used for chronic respiratory disease in chickens, Mycoplasma pneumonia and Haemophilus pleuropneumonia in pigs, and also for dysentery caused by Leptospira densa in pigs.
● Tiamulin fumarate has good antibacterial activity against a variety of gram-positive cocci including most staphylococci and streptococci (except group D streptococci) and a variety of mycoplasma and some spirochetes. However, it has weak antibacterial activity against certain negative bacteria, with the exception of Haemophilus spp. and certain strains of Escherichia coli and Klebsiella.
| Item | Specification | Result |
| Appearance | White or almost white crystal powder | Complies |
| Identification | HPLC: The retention time obtained from the test solution corresponding to thatobtained from the standard solution | 0.2% 0.06% |
| IR: IR of the sample corresponding to that reference standard | Complies | |
| Color and clarity of solution | The solution should be clear and colorless, and the absorbance at 400nm and 650nm are not greater than 0.150 and 0.030 | 99.8% |
| Specific rotation | +24~28° | Complies |
| PH | 3.1~4.1 | 0.12%~0.09% |
| Loss on drying | ≤ 0.5% | Complies |
| Melting point | 143~149°C | 0.05ppm |
| Fumarate content | 83.7~87.3mg | 0.05ppm |
| Residue on ignition | ≤ 0.1% | 0.05ppm |
| Heavy metals | ≤ 0.001% | Complies |
| Solvent residue | ≤ 0.5% | Complies |
| Chromatographic purity | Any identified impurity ≤ 1.0% | |
| Any unidentified impurity ≤ 0.5% | Complies | |
| Total impurities≤ 2.0% | Complies | |
| Assay (on dried basis) | 98.0~102.0% | Complies |
| Salmonella | Negative | Complies |
