Spectinomycin Hydrochloride(21736-83-4)
Product Description
● Spectinomycin is an aminocyclitol antibiotic, closely related to the aminoglycosides, produced by the bacterium Streptomyces spectabilis.
● Spectinomycin hydrochloride is a new parenteral antibiotic prepared from Streptomyces spectabilis. Spectinomycin (HCl) is structurally related to aminoglycosides. Spectinomycin lacks amino sugar and glycosidic bonds. Spectinomycin has moderate antibacterial activity against many gram positive and gram negative bacteria but Spectinomycin (HCl) is especially effective against Niesseria gonorrhoeae.
Item | Specifications | Results |
Characters-appearance-solubility | A white or almost white powder,slightly hygroscopic,freely soluble in water,very slightlySoluble in ethanol(96%) | White powder,slightly hygroscopicConform |
Identification | Infrared abaorption spectrophotometryGive reaction(a)of chlorides | Conform
Conform |
Appearance of solution | The solution is clearThe solution is colorless | Conform
Conform |
PH | 3.8~5.6 | 4.2 |
Specific optical rotation | +15°~+21° | +19° |
Water | 16.0%~20.0% | 17.6% |
Sulfated ash | Maximum 1.0% | 0.1% |
Related substances | Mazimum1.0% | Less than 1.0% |
Assay(based on anhydrous substance by GC) | 95.0%~100.5% of C14H24N2O7.2HCL | 96.3% |
Assay(based on hydrous substance,by GC) | - | 79.34% |
Potency(based on hydrous substance,by GC) | - | 651IU/mg |
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