Metronidazole(443-48-1)
Product Description
● Metronidazole has strong effectto most anaerobic bacteria, used inthetreatment of amebiasis,trichomoniasis and anaerobic infections.
● Indications: for the treatment of intestinal and parenteral amebiasis (such as amoebic liver abscess, pleural amebiasis, etc.). but also for the treatment of vaginal trichomoniasis, coccidiosis pouch and cutaneous leishmaniasis, Guinea worm infection. is still widely used in the treatment of anaerobic infections.
| Name of product | Metronidazole | |
| Expiry Date | 4 years | |
| ITEMS | STANDARDS | RESULTS |
| Characteristics | a white or yellowish crystalline powder, slighting sobube in water, in acetone, in alcohol and in methylene, chloride, veryslightly solube in ether | COMPLY |
| Identification | a) Melting point 159-163℃ | 161.1-161.3℃ |
| b) Specific absorbance 365-395 | b) 375 | |
| c) IR | c) COMPLY | |
| d) The solution gives the reaction of primary aromatic amines | d) COMPLY | |
| Appearance of solution | SUSPENSION Ⅱ | COMPLY |
| AND SOLUTION GY6 | ||
| Related substances | Impurity:0.1MAX | 0.02% |
| Total impurity:0.2MAX | 0.06% | |
| Heavy Metal | 20PPM MAX | <20PPM |
| Loss on drying | 0.5% MAX | 0.19% |
| Particle size | 40-80mesh | COMPLY |
| Assay | 99.0%-101.0% | 99.4% |
| Item | Standards | Result |
| Identification | positive reaction | positive reaction |
| Melting point | 159~163℃ | 160.5~160.9℃ |
| Loss on drying | 0.5% MAX | 0.18% |
| Sulphated ash | 0.1% MAX | 0.06% |
| Heavy metal | 20PPM MAX | <20ppm |
| Appearance of solution | pass | pass |
| Related substances | pass | pass |
| Specific absorbance | 365 ~389 | 378 |
| Simple Impurities | 0.1% MAX | 0.03% |
| Total Impurities | 0.2% MAX | 0.10% |
| Assay | 99.0%~101.0% C6H9N3O3 | 99.85% C6H9N3O3 |
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