Lincomycin Hydrochloride (859-18-7)
Product Description
● Lincomycin hydrochloride mainly has strong antibacterial effect on Gram-positive bacteria, some anaerobic bacteria and mycobacteria, with narrower antibacterial spectrum than erythromycin.
● Lincomycin hydrochloride mainly has strong antibacterial effect on Gram-positive bacteria, some anaerobic bacteria and mycobacteria, with narrower antibacterial spectrum than erythromycin.
● Lincomycin hydrochloride is mainly used to treat various infections caused by gram-positive bacteria, especially penicillin-resistant gram-positive bacteria, chronic respiratory disease of poultry caused by mycoplasma, wheezing disease of pigs, anaerobic bacterial infections such as necrotizing enteritis of chickens, etc. It is also used to treat dysentery of pigs, toxoplasmosis and actinomycosis of dogs and cats.
| Items | Standards | Results | Conclusions |
| Characters | A white or almost white crystalline powder | Almost white crystalline powder | Conform |
| Identification | A. 1R: consistent with that obtained with Lincomycin Hydrochloride reference standard. | A. IR: consistent with that obtained with Lincomycin Hydrochloride reference standard. | Conform |
| Specific optical rotation | 136° 〜149° | 142° | Conform |
| Crystallinity | Conforming | Conforming | Conform |
| ［pH］ | 3.2 〜5.4 | 4.4 | Conform |
| Water | 3.1% 〜5.8% | 3.9% | Conform |
| Lincomycin B | ≤ 4.8% | 3.0% | Conform |
| Bacterial endotoxins | ≤ 0.5 lU/mg | Less than 0.5 lU/mg | Conform |
| Residual solvents | n-Butanol: Not more than 500ppm | 269ppm | Conform |
| Octanol: Not more than 2ppm | BDL | ||
| Assay (On anhydrous basis, lincomycin) | ≤ 790 ug/mg. | 879ug/mg | Conform |
