Glycerol Kinase(GK)
Description
The protein encoded by this gene belongs to the FGGY kinase family. This protein is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Mutations in this gene are associated with glycerol kinase deficiency (GKD). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
This enzyme is used for diagnostic tests for the determination of triglycerides together with Glycerol-3-phosphate Oxidase.
Chemical Structure
Reaction Principle
Glycerol + ATP→ Glycerol -3- phosphate + ADP
Specification
| Test Items | Specifications |
| Description | White to slightly yellowish amorphous powder, lyophilized |
| Activity | ≥15U/mg |
| Purity(SDS-PAGE) | ≥90% |
| Solubility(10mg powder/ml) | Clear |
| Catalase | ≤0.001% |
| Glucose oxidase | ≤0.01% |
| Uricase | ≤0.01% |
| ATPase | ≤0.005% |
| Hexokinase | ≤0.01% |
Transportation and storage
Transportation: Shipped under -15°C
Storage : Store at -20°C(Long term), 2-8°C(Short term)
Recommended re-test Life: 18 months
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